Studies on Host Specificity of Bacteriophage

Studies on Bacteriophage and Metabolic Identification of Brucella Strains

STUDIES ON THE TISSUE SPECIFICITY OF COLONY STIMULATING FACTOR

In this study granulocyte-macrophage colony stimulating factor (CSF) was prepared from rabbit and guinea pig lung tissues. The biological activity of these CSFs was measured on semisolid agar culture and compared with those of mouse and rat. Weight of animals, incubation time and cross-reactivity of CSFs with different bone marrow sources were also investigated. The results showed that both...

Allelic and Nonallelic Genes Controlling Host Specificity in a Bacteriophage.

ACTERIA infected with any two independently arising r (plaque type) B mutants of the bacterial virus T2H have been found, as a rule, to yield wild-type and double-mutant individuals among the viral progeny ( HERSHEY and ROTMAN 1948). This result has been interpreted in terms of recombination among nonallelic genetic-factors, and it is permissible to speak of the test in which bacteria are infec...

Studies on Bacteriophage

Phase I and Phase II Sh. sonnei exhibit differences in their susceptibility to the T series of bacteriophages. Both microorganisms are lysed by T(2) and T(6), but only the Phase II bacillus is lysed by T(3), T(4), and T(7). Lysis of the Phase I or Phase II bacillus by T(2) or T(6) is not inhibited by the homologous type-specific antigen. In the presence of an appropriate cofactor, however, the ...

Studies on Streptococcus Bacteriophage

A series of experiments was carried out on various strains of streptococci in order to ascertain the changes which bacteriophage produces in the phenomena of agglutination of these organisms. The results can be placed in the following categories. 1. Loss of specific agglutinability was observed with partial and with what appeared as complete loss of specific agglutinin absorption and agglutinog...